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Molbank, Vol. 2018, Article 1001: (E)-3-[3-(2-Butoxyquinolin-3-yl)acryloyl]-2-hydroxy-4H-chromen-4-one

Molbank, Vol. 2018, Article 1001: (E)-3-[3-(2-Butoxyquinolin-3-yl)acryloyl]-2-hydroxy-4H-chromen-4-one

Molbank doi: 10.3390/M1001

Authors: Rodrigo Abonia Luisa Gutiérrez Jairo Quiroga Braulio Insuasty

The coumarinyl-quinolinylchalcone hybrid (E)-3-[3-(2-butoxyquinolin-3-yl)acryloyl]-2-hydroxy-4H-chromen-4-one 3b was prepared in good yield from a Claisen-Schmidt condensation reaction between 3-acetyl-4-hydroxy-2H-chromen-2-one 1 and 2-butoxyquinoline-3-carbaldehyde 2 in methanol at reflux and catalyzed by KOH pellets. The structure of the synthesized compound 3b was fully confirmed by FTIR-ATR, (1D and 2D) NMR experiments, EIMS and elemental analysis.

Authors:   Abonia, Rodrigo ; Gutiérrez, Luisa ; Quiroga, Jairo ; Insuasty, Braulio
Journal:   Molbank
Volume:   2018
edition:   3
Year:   2018
Pages:   1001
DOI:   10.3390/M1001
Publication date:   21-Jun-2018
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