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Lasso peptides: chemical approaches and structural elucidation

The discovery and development of novel constrained peptides that combine the advantages of therapeutic proteins with those of small molecules has partially prompted the re-emergence of peptides as therapeutics. In this regard, lasso peptides are characterized by both the selectivity and potency of larger protein bi Chemical biology in OBC

Authors:   Helena Martin-Gómez; Judit Tulla-Puche
Journal:   Organic & Biomolecular Chemistry
DOI:   10.1039/C8OB01304G
Facts, background information, dossiers
  • peptides
  • therapeutics
  • therapeutic proteins
  • small molecules
  • selectivity
  • chemical biology
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