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New development in the enantioselective synthesis of spiro compounds

The enantioselective synthesis of spirocycles has long been pursued by organic chemists. Despite their unique 3D properties and presence in several natural products, the difficulty in their enantioselective synthesis makes them underrepresented in pharmaceutical libraries. Since the first pioneering reports of the

Authors:   Aishun Ding; Marta Meazza; Hao Guo; Jung Woon Yang; Ramon Rios
Journal:   Chemical Society Reviews
DOI:   10.1039/C6CS00825A
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  • enantioselective synthesis
  • natural products
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