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MRI and luminescence detection of Zn2+ with a lanthanide complex–zinc finger peptide conjugate

A bioinspired probe based on a zinc finger peptide functionalized by a lanthanide(iii)-DOTA monoamide complex turns out to be active for both luminescence and MRI detection of Zn2+, depending on the lanthanide cation. A mechanism for MRI-based detection is proposed.

Authors:   Manon Isaac; Agnès Pallier; Frédéric Szeremeta; Pierre-Alain Bayle; Laurent Barantin; Célia S. Bonnet; Olivier Sénèque
Journal:   Chemical Communication
Volume:   54
edition:   53
Pages:   7350
DOI:   10.1039/C8CC04366C
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