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Engineering strategies for rational polyketide synthase design

Covering: mid 1990s to 2018Over the last two decades, diverse approaches have been explored to generate new polyketides by engineering polyketide synthases (PKSs). Although it has been proven possible to produce new compounds by designed PKSs, engineering strategies failed to make polyketides available via widely a

Authors:   Maja Klaus; Martin Grininger
Journal:   Natural Product Reports
DOI:   10.1039/C8NP00030A
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