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Protein-protein interactions of Human Glyoxalase II: findings of a reliable docking protocol

Glyoxalase II (GlxII) is an antioxidant glutathione-dependent enzyme, which catalyzes the hydrolysis of S-D-lactoylglutathione to form D-lactic acid and glutathione (GSH). The last product is the most important thiol reducing agent present in all eukaryotic cells that have mitochondria and chloroplasts. It i Chemical biology in OBC

Authors:   Roberta Galeazzi; Emiliano Laudadio; Emanuele Falconi; Luca Massaccesi; Luisa Ercolani; Giovanna Mobbili; Cristina Minnelli; Andrea Scirè; Laura Cianfruglia; Tatiana Armeni
Journal:   Organic & Biomolecular Chemistry
DOI:   10.1039/C8OB01194J
Facts, background information, dossiers
  • glutathione
  • protein interactions
  • mitochondria
  • chemical biology
  • cells
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