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Towards Mapping Electrostatic Interactions between Kdo2-Lipid A and Cationic Antimicrobial Peptides via Ultraviolet Photodissociation Mass Spectrometry

Cationic antimicrobial peptides (CAMPs) have known to act as multi-modal weapons against Gram-negative bacteria. As a new approach to investigate the nature of the interactions between CAMPs and the surfaces of bacteria, native mass spectrometry and two MS/MS strategies (ultraviolet photodissociation (UVPD)

Authors:   Christopher M Crittenden; Lindsay Jane Morrison; Mignon D Fitzpatrick; Allison P Myers; Elisa T Novelli; Jake Rosenberg; Lucas Akin; Vishnu Srinivasa; Jason B. Shear; Jennifer S Brodbelt
Journal:   Analyst
DOI:   10.1039/C8AN00652K
Facts, background information, dossiers
  • interactions
  • bacteria
  • photodissociation
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