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Synthesis of aminomethylated 4-fluoropiperidines and 3-fluoropyrrolidines

Guido Verniest, Karel Piron, Eva Van Hende, Jan Willem Thuring, Gregor Macdonald, Frederik Deroose, Norbert De Kimpe
(Communication from Org. Biomol. Chem.)
Guido Verniest, Org. Biomol. Chem., 2010, DOI: 10.1039/c003380d
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Ontology Terms: calcium channel activity; piperidines; antibacterial agent; benzyl group; pyrrolidines; pyrrolidinone; azides; azido group; agrochemical; antidepressant; analgesic; cyanohydrin; acetyl group; amino group; fluoropyrrolidine; agonist; antagonist; cyano group; hydroxypiperidine; piperidone; tert-butoxycarbonyl group; Gabriel synthesis; protecting group; 1H nuclear magnetic resonance spectroscopy; chromatography; fluorination; pharmaceutical; N-benzylation; O-tosylation; hydrogenation; purification
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Authors:   Guido Verniest; Karel Piron; Eva Van Hende; Jan Willem Thuring; Gregor Macdonald; Frederik Deroose; Norbert De Kimpe
Journal:   Organic & Biomolecular Chemistry
Volume:   8
edition:   11
Year:   2010
Pages:   2509
DOI:   10.1039/C003380D
Publication date:   21-Apr-2010
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