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An efficient entry to 1,2-benzisoxazoles via 1,3-dipolar cycloaddition of in situ generated nitrile oxides and benzyne

Christian Spiteri, Christopher Mason, Fengzhi Zhang, Dougal J. Ritson, Pallavi Sharma, Steve Keeling, John E. Moses
(Paper from Org. Biomol. Chem.)
Christian Spiteri, Org. Biomol. Chem., 2010, DOI: 10.1039/b927235f
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Ontology Terms: aromatic compound; anticonvulsant; inorganic molecular entity; benzyne; aryne; heterocyclic compound; solvent; 1,3-dipolar cycloaddition; acetate ester; benzotriazole; nitrile oxide; trimethylsilyl group; high-resolution mass spectrometry; pulsed nuclear magnetic resonance spectroscopy; infrared absorption spectroscopy; Fourier transform infrared spectroscopy; 1H nuclear magnetic resonance spectroscopy; carbon-13 nuclear magnetic resonance spectrum; column chromatography; mass spectrum; nuclear magnetic resonance spectrum; spectrum; thin-layer chromatography; benzisoxazole; indolyl group; experimental method output; pharmaceutical; spectrometer; [2+2] cycloaddition; cyclization; cycloaddition; cycloelimination; purification
Primary Compounds:

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Authors:   Christian Spiteri; Christopher Mason; Fengzhi Zhang; Dougal J. Ritson; Pallavi Sharma; Steve Keeling; John E. Moses
Journal:   Organic & Biomolecular Chemistry
Volume:   8
edition:   11
Year:   2010
Pages:   2537
DOI:   10.1039/B927235F
Publication date:   07-Apr-2010
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