The Effect of Sequential Fractionation Technique on the Various Efficacies of Pomegranate (Punica granatum L.)
The pomegranate (Punica granatum L.) is a fruit-bearing deciduous shrub. Various parts of this plant are used in the treatment of dyspepsia, bronchitis, hypotensive, throat inflammation, etc. and its nutritional value has well been accepted. In the present study, antioxidant and antimicrobial efficacy of different solvent fractions of P. granatum leaves was investigated. Fractionation was done sequentially in Soxhlet apparatus, using various solvents like petroleum ether, toluene, ethyl acetate, acetone, and water. Antioxidant activity was evaluated by 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging assay, superoxide anion radical scavenging assay, and reducing capacity assessment. Total phenol and flavonoid content was also measured. The antimicrobial activity was assessed by agar well diffusion method against some of the tested food borne, pathogenic, and skin disease causing microorganisms. Antiulcer activity of the P. granatum acetone fraction (PGA) was evaluated using ethanol-induced gastric ulcer model. The PGA had maximum phenol content and had higher antioxidant activity. The PGA showed better DPPH free radical and superoxide anion radical scavenging activity than that of the standards. The results demonstrated that acetone fraction had potent gastroprotective and antisecretory effects. This study suggests that sequential fractionation technique is an excellent technique of extracting bioactive components of this plant at least. This study also demonstrated that PGA can serve as a potential natural source for use in food, nutraceutical, and pharmaceutical industry.
Plant parasitic nematodes are the most destructive group of plant pathogens worldwide and their control is extremely challenging. Plant Essential oils (EOs) and their constituents have a great potential in nematode control since they can be developed for use as nematicides themselves or can ... more
For over a century, ulcer has been a major cause of morbidity and mortality. Its treatment has progressed from vagotomy to proton pump inhibitors. However, the drugs used produce many adverse effects and are less effective than they ought to be. Therefore, there is a growing interest in alt ... more
Endophytic fungi are ubiquitous organisms found in the plants, residing intercellular or intracellular, at least for a portion of their lives without causing apparent symptoms of infection. Almost all plants are known to harbor endophytes. The choice of the plant to be used for exploring en ... more
Springer Nature published its first machine-generated book, compiled using an algorithm developed by researchers from Goethe University. This collaboration broke new ground with the first machine-generated book to be published by a scholarly publisher.
The book is available as a free downl ... more
Inflatable toys and swimming aids, like bathing rings and arm bands, often have a distinctive smell which could indicate that they contain a range of potentially hazardous substances. Some of these compounds, which include carbonyl compounds, cyclohexanone, phenol and isophorone, might be c ... more
Graphene, the one-atom-thick material made of carbon atoms, still holds some unexplained qualities, which are important in connection with electronic applications where high-conductivity matters, ranging from smart materials that collectively respond to external stimuli in a coherent, tunab ... more
Springer is a leading global scientific, technical and medical portfolio, providing researchers in academia, scientific institutions and corporate R&D departments with quality content through innovative information, products and services. more