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Photoinduced protein modifications by methylene blue and naproxen

HPLC and emission spectroscopy were used to investigate UVA photosensitization of methylene blue (MB) or naproxen (NAP) towards bovine serum albumin (BSA). In addition, time resolved singlet oxygen measurements were carried out. The most stable drug:protein adducts stoichiometry of MB-BSA (1:1) and NAP-BSA (

Authors:   Guido de Guidi; Alfio Catalfo; Giuseppina Bracchitta
Journal:   Photochemical & Photobiological Sciences
DOI:   10.1039/C2PP25067E
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