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Improved anti-proliferative effect of doxorubicin-containing polymer nanoparticles upon surface modification with cationic groups

Polymer nanoparticles (PNPs) possessing a high density of drug payload have been successfully stabilized against aggregation in biological buffers after amine modification, which renders these PNPs positively charged. The resulting charge-stabilized PNPs retain their original narrow particle size distributions and

Authors:   Sai Archana Krovi; Elden P. Swindell; Thomas V. O'Halloran; SonBinh T. Nguyen
Journal:   Journal of Materials Chemistry
DOI:   10.1039/C2JM35420A
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