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Lab-on-a-chip for high frequency acoustic characterization

This paper presents an acoustofluidics platform for elastic characterization of biological samples using ultra high frequency (∼1GHz) ultrasonic bulk acoustic waves (BAW). The propagation of bulk acoustic waves in a plane parallel to the surface of a silicon wafer was controlled using 45° acoustic mirrors, thus leading to the development of real time biosensing applications in a microchannel fabricated using ICP technology. To validate the design and technology of the silicon and PDMS-based platform, the propagation of bulk acoustic waves through the microfluidic channel was studied. This lab-on–a-chip platform was used to characterize different concentrations of chemical solutions in the microfluidic channel and detect latex particles passing through the channel.

Authors:   Jiaming Gao, Julien Carlier, Shengxiang Wang, Pierre Campistron, Dorothee Callens, Shishang Guo, Xingzhong Zhao, Bertrand Nongaillard
Journal:   Sensors and Actuators B: Chemical
Year:   2012
DOI:   10.1016/j.snb.2012.11.037
Publication date:   26-Nov-2012
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