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Energy-dependent motion of TonB in the Gram-negative bacterial inner membrane [Microbiology]

Gram-negative bacteria acquire iron with TonB-dependent uptake systems. The TonB–ExbBD inner membrane complex is hypothesized to transfer energy to outer membrane (OM) iron transporters. Fluorescence microscopic characterization of green fluorescent protein (GFP)-TonB hybrid proteins revealed an unexpected, restricted localization of TonB in the cell envelope. Fluorescence polarization measurements demonstrated motion...

Authors:   Lorne D. Jordan; Yongyao Zhou; Chuck R. Smallwood; Yoriko Lill; Ken Ritchie; Wai Tak Yip; Salete M. Newton; Phillip E. Klebba
Journal:   Proceedings of the National Academy of Sciences current issue
Volume:   110
edition:   28
Year:   2013
Pages:   11553
DOI:   10.1073/pnas.1304243110
Publication date:   09-Jul-2013
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