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ChemInform Abstract: Improved and Scalable Preparation of 6‐Bromo‐4‐chlorothieno[2,3‐d]pyrimidine.


The title compound (VII), a useful precursor for the synthesis of a library of thienopyrimidine‐based kinase inhibitors, is obtained starting from cheap bulk chemicals in four steps.

Authors:   S. Bugge, E. M. Skjoensfjell, F. B. Willumsen, E. Sundby, B. H. Hoff
Journal:   ChemInform
Volume:   46
edition:   16
Year:   2015
Pages:   no
DOI:   10.1002/chin.201516255
Publication date:   02-Apr-2015
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