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On-line determination by small angle X-ray scattering of the shape of hen egg white lysozyme immediately following elution from a hydrophobic interaction chromatography column

This study documents the use of an integrated approach, involving on-line hydrophobic interaction chromatography interfaced with Small Angle X-ray Scattering (HIC–SAXS) measurements, to monitor the conformational status of proteins immediately upon elution from a chromatographic column operated at different tempera

Authors:   Chadin Kulsing; Andras Z. Komaromy; Reinhard I. Boysen; Milton T. W. Hearn
Journal:   Analyst
DOI:   10.1039/C6AN00851H
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