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1,838 Newest Publications in annals of the new york academy of sciences

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Designing the stem cell microenvironment for guided connective tissue regeneration

20-Dec-2017 | Danielle R. Bogdanowicz, Helen H. Lu, Annals of the New York Academy of Sciences, 2017

Abstract Adult mesenchymal stem cells (MSCs) are an attractive cell source for regenerative medicine because of their ability to self‐renew and their capacity for multilineage differentiation and tissue regeneration. For connective tissues, such as ligaments or tendons, MSCs are vital to the ...

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Inflammatory biomarkers of low back pain and disc degeneration: a review

20-Dec-2017 | Aysha N. Khan, Hayley E. Jacobsen, Jansher Khan, Christopher G. Filippi, Mitchell Levine, Ronald A. Lehman, K. Danie ..., Annals of the New York Academy of Sciences, 2017

Abstract Biomarkers are biological characteristics that can be used to indicate health or disease. This paper reviews studies on biomarkers of low back pain (LBP) in human subjects. LBP is the leading cause of disability, caused by various spine‐related disorders, including intervertebral disc ...

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Current perspectives on biological approaches for osteoarthritis

20-Dec-2017 | Kaitlyn E. Whitney, Andrea Liebowitz, Ioanna K. Bolia, Jorge Chahla, Sudheer Ravuri, Thos A. Evans, Marc J. Philippo ..., Annals of the New York Academy of Sciences, 2017

Abstract Musculoskeletal injuries that disrupt the structure and function of diarthrodial joints can cause permanent biomechanical alterations and lead to a more severe, chronic condition. Despite advancements that have been made to restore tissue function and delay the need for joint ...

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Bone quality changes associated with aging and disease: a review

20-Dec-2017 | Adele L. Boskey, Laurianne Imbert, Annals of the New York Academy of Sciences, 2017

Abstract Bone quality encompasses all the characteristics of bone that, in addition to density, contribute to its resistance to fracture. In this review, we consider changes in architecture, porosity, and composition, including collagen structure, mineral composition, and crystal size. These ...

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Tissue‐specific endothelial cells: a promising approach for augmentation of soft tissue repair in orthopedics

20-Dec-2017 | Amir Lebaschi, Yusuke Nakagawa, Susumu Wada, Guang‐Ting Cong, Scott A. Rodeo, Annals of the New York Academy of Sciences, 2017

Abstract Biologics are playing an increasingly significant role in the practice of modern medicine and surgery in general and orthopedics in particular. Cell‐based approaches are among the most important and widely used modalities in orthopedic biologics, with mesenchymal stem cells and other ...

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Pitfalls in using fluorescence tagging of nanomaterials: tecto‐dendrimers in skin tissue as investigated by Cluster‐FLIM

06-Oct-2017 | Pierre Volz, Priscila Schilrreff, Robert Brodwolf, Christopher Wolff, Johannes Stellmacher, Jens Balke, Maria J. Mor ..., Annals of the New York Academy of Sciences, 2017

Abstract Targeted topical application promises high drug concentrations in the skin and low systemic adverse effects. To locate drugs and drug‐delivery systems like nanocarriers, fluorescent dyes are commonly used as drug surrogates or nanocarrier labels in micrographs of tissue sections. ...

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Pitfalls in using fluorescence tagging of nanomaterials: tecto‐dendrimers in skin tissue as investigated by Cluster‐FLIM

06-Oct-2017 | Pierre Volz, Priscila Schilrreff, Robert Brodwolf, Christopher Wolff, Johannes Stellmacher, Jens Balke, Maria J. Mor ..., Annals of the New York Academy of Sciences, 2017

Abstract Targeted topical application promises high drug concentrations in the skin and low systemic adverse effects. To locate drugs and drug‐delivery systems like nanocarriers, fluorescent dyes are commonly used as drug surrogates or nanocarrier labels in micrographs of tissue sections. ...

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Does phytoestrogen supplementation improve cognition in humans? A systematic review

25-Sep-2017 | Jay Jay Thaung Zaw, Peter Ranald Charles Howe, Rachel Heloise Xiwen Wong, Annals of the New York Academy of Sciences, 2017

Abstract Recent evidence indicates that resveratrol, a phytoestrogen, can improve cognitive function in postmenopausal women by enhancing cerebral vasodilator responsiveness. We examine the effects of phytoestrogen supplementation on cognition and compare resveratrol with other phytoestrogens. ...

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Does phytoestrogen supplementation improve cognition in humans? A systematic review

25-Sep-2017 | Jay Jay Thaung Zaw, Peter Ranald Charles Howe, Rachel Heloise Xiwen Wong, Annals of the New York Academy of Sciences, 2017

Abstract Recent evidence indicates that resveratrol, a phytoestrogen, can improve cognitive function in postmenopausal women by enhancing cerebral vasodilator responsiveness. We examine the effects of phytoestrogen supplementation on cognition and compare resveratrol with other phytoestrogens. ...

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Resveratrol and cancer treatment: updates

25-Sep-2017 | Zhengdong Jiang, Ke Chen, Liang Cheng, Bin Yan, Weikun Qian, Junyu Cao, Jie Li, Erxi Wu, Qingyong Ma, Wei Yang, Annals of the New York Academy of Sciences, 2017

Abstract Cancer, a growing health problem worldwide, affects millions of people every year. The overall survival rates of most cancers have been prolonged owing to the efforts of clinicians and scientists. However, some tumors develop resistance to chemoradiotherapeutic agents, and the cancer ...

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