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563 Newest Publications in bioorganic chemistry

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New fluorescent rosamine chelator showing promising antibacterial activity against Gram-positive bacteria

11-Jun-2018 | Author(s): Ângela Novais, Tânia Moniz, Ana Rita Rebelo, Ana M.G. Silva, Maria Rangel, Luísa Peixe, Bioorganic Chemistry, 2018

Publication date: September 2018 Source:Bioorganic Chemistry, Volume 79 Author(s): Ângela Novais, Tânia Moniz, Ana Rita Rebelo, Ana M.G. Silva, Maria Rangel, Luísa Peixe The restricted number of antibiotics to treat infections caused by common multidrug resistant bacterial ...

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Supramolecular nanofiber of pyrene-lactose conjugates and its two-photon fluorescence imaging

11-Jun-2018 | Author(s): Qian Sun, Hong-Yu Zhu, Jun-Fang Wang, Xiao Chen, Ke-Rang Wang, Xiao-Liu Li, Bioorganic Chemistry, 2018

Publication date: September 2018 Source:Bioorganic Chemistry, Volume 79 Author(s): Qian Sun, Hong-Yu Zhu, Jun-Fang Wang, Xiao Chen, Ke-Rang Wang, Xiao-Liu Li A lactose modified pyrene derivative (Py-Lac) was synthesized, with which novel twisted supramolecular nanofibers in ...

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Discovery of potent α-glucosidase inhibitor flavonols: Insights into mechanism of action through inhibition kinetics and docking simulations

11-Jun-2018 | Author(s): Didem Şöhretoğlu, Suat Sari, Burak Barut, Arzu Özel, Bioorganic Chemistry, 2018

Publication date: September 2018 Source:Bioorganic Chemistry, Volume 79 Author(s): Didem Şöhretoğlu, Suat Sari, Burak Barut, Arzu Özel Beside other pharmaceutical benefits, flavonoids are known for their potent α-glucosidase inhibition. In the present study, we investigated ...

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Multi-targetable chalcone analogs to treat deadly Alzheimer’s disease: Current view and upcoming advice

11-Jun-2018 | Author(s): Xu Zhang, K.P. Rakesh, S.N.A. Bukhari, Moku Balakrishna, H.M. Manukumar, Hua-Li Qin, Bioorganic Chemistry, 2018

Publication date: October 2018 Source:Bioorganic Chemistry, Volume 80 Author(s): Xu Zhang, K.P. Rakesh, S.N.A. Bukhari, Moku Balakrishna, H.M. Manukumar, Hua-Li Qin The complications of Alzheimer’s disease AD were deadly dangerous cause of neurodegenerative disorders connected ...

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Drechmerin H, a novel 1(2), 2(18)-diseco indole diterpenoid from the fungus Drechmeria sp. as a natural agonist of human pregnane X receptor

11-Jun-2018 | Author(s): Jian-Chao Zhao, Zhi-Lin Luan, Jia-Hao Liang, Zhong-Bin Cheng, Cheng-Peng Sun, Ya-Li Wang, Men ..., Bioorganic Chemistry, 2018

Publication date: September 2018 Source:Bioorganic Chemistry, Volume 79 Author(s): Jian-Chao Zhao, Zhi-Lin Luan, Jia-Hao Liang, Zhong-Bin Cheng, Cheng-Peng Sun, Ya-Li Wang, Meng-Yue Zhang, Tian-Yuan Zhang, Yong Wang, Tian-Mei Yang, Ying-Ying Wu, Yi-Xuan Zhang, ...

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Novel 3-phenylcoumarin–lipoic acid conjugates as multi-functional agents for potential treatment of Alzheimer's disease

11-Jun-2018 | Author(s): Leili Jalili-Baleh, Hamid Nadri, Hamid Forootanfar, Alireza Samzadeh-Kermani, Tuba Tüylü Küçükk ..., Bioorganic Chemistry, 2018

Publication date: September 2018 Source:Bioorganic Chemistry, Volume 79 Author(s): Leili Jalili-Baleh, Hamid Nadri, Hamid Forootanfar, Alireza Samzadeh-Kermani, Tuba Tüylü Küçükkılınç, Beyza Ayazgok, Mahban Rahimifard, Maryam Baeeri, Mohsen Doostmohammadi, Loghman ...

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Steroids from Ganoderma sinense as new natural inhibitors of cancer-associated mutant IDH1

11-Jun-2018 | Author(s): Mengzhu Zheng, Ruotian Tang, Yue Deng, Kaiyin Yang, Lixia Chen, Hua Li, Bioorganic Chemistry, 2018

Publication date: September 2018 Source:Bioorganic Chemistry, Volume 79 Author(s): Mengzhu Zheng, Ruotian Tang, Yue Deng, Kaiyin Yang, Lixia Chen, Hua Li Isocitrate dehydrogenase (IDH) is one of the key enzymes in the tricarboxylic acid cycle, and IDH mutations have been ...

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A novel derivatives of thiazol-4(5H)-one and their activity in the inhibition of 11β-hydroxysteroid dehydrogenase type 1

11-Jun-2018 | Author(s): Renata Studzińska, Renata Kołodziejska, Daria Kupczyk, Wojciech Płaziński, Tomasz Kosmalski, Bioorganic Chemistry, 2018

Publication date: September 2018 Source:Bioorganic Chemistry, Volume 79 Author(s): Renata Studzińska, Renata Kołodziejska, Daria Kupczyk, Wojciech Płaziński, Tomasz Kosmalski 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) is an enzyme that catalyzes the conversion of inactive ...

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Structure-activity relationships of rationally designed AMACR 1A inhibitors

11-Jun-2018 | Author(s): Maksims Yevglevskis, Guat L. Lee, Amit Nathubhai, Yoana D. Petrova, Tony D. James, Michael D. ..., Bioorganic Chemistry, 2018

Publication date: September 2018 Source:Bioorganic Chemistry, Volume 79 Author(s): Maksims Yevglevskis, Guat L. Lee, Amit Nathubhai, Yoana D. Petrova, Tony D. James, Michael D. Threadgill, Timothy J. Woodman, Matthew D. Lloyd α-Methylacyl-CoA racemase (AMACR; P504S) is a ...

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Identification of novel indole based heterocycles as selective estrogen receptor modulator

11-Jun-2018 | Author(s): Ramit Singla, Kunal Prakash, Kunj Bihari Gupta, Shishir Upadhyay, Monisha Dhiman, Vikas Jaitak, Bioorganic Chemistry, 2018

Publication date: September 2018 Source:Bioorganic Chemistry, Volume 79 Author(s): Ramit Singla, Kunal Prakash, Kunj Bihari Gupta, Shishir Upadhyay, Monisha Dhiman, Vikas Jaitak In the present study, we have designed and synthesized indole derivatives by coalescing the indole ...

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