My watch list  

9,059 Newest Publications in organic & biomolecular chemistry


You can refine your search further. Select from the filter options on the left to narrow down your results.

Palladium-catalyzed selective synthesis of 3,4-dihydroquinazolines from electron-rich arylamines, electron-poor arylamines and glyoxalates

03-Jul-2018 | Chao Wu; Jie Wang; Xing-Yu Zhang; Guo-Kai Jia; Zhong Cao; Zilong Tang; Xianyong Yu; Xinhua Xu; Wei-Min He, Organic & Biomolecular Chemistry, 2018

A simple palladium-catalyzed selective synthesis of structurally diverse 3,4-dihydroquinazolines from electron-rich arylamines, electron-poor arylamines and glyoxalates has been developed under mild conditions. This reaction is carried out in a tandem manner constituted by the condensation of ...


Synthesis of acyloxyl pyrazolines by copper-mediated aminoacyloxylation of unsaturated ketohydrazones

27-Jun-2018 | Manman Chen; Lin Qi; Jiamin Chen; Peixing Ren; Jie Du; Lijing Wang; Wei Li, Organic & Biomolecular Chemistry, 2018

An efficient and step-economical copper-mediated intra-/intermolecular aminoacyloxylation of β, γ-unsaturated hydrazones has been developed. Copper carboxylates serve as both reaction promoter and carboxylate source in these easily conducted reactions. This method provides straightforward access ...


Pd-Catalyzed diastereoselective [3 + 2] cycloaddition of vinylcyclopropanes with sulfamate-derived cyclic imines

27-Jun-2018 | Qijun Wang; Chang Wang; Wangyu Shi; Yumei Xiao; Hongchao Guo, Organic & Biomolecular Chemistry, 2018

The palladium-catalyzed diastereoselective [3 + 2] cycloaddition reaction of vinylcyclopropanes with sulfamate-derived cyclic imines worked efficiently under mild reaction conditions, providing 2,3-dihydrobenzo[e]pyrrolo[1,2-c][1,2,3]oxathiazine 5,5-dioxide derivatives in good to excellent yields.


Synthesis of Hydrophobic Insulin-based Peptides Using a Helping-Hand Strategy

26-Jun-2018 | Maria Disotuar; Mark E Petersen; Jason M Nogueira; Michael S Kay; Danny Hung-chieh Chou, Organic & Biomolecular Chemistry, 2018

The introduction of solid-phase peptide synthesis in the 1960’s improved the chemical synthesis of both the A- and B-chains of insulin and insulin analogs. However, the subsequent elaboration of the synthetic peptides to generate active hormones continues to be difficult and complex due in part ...


Second-order asymmetric transformation; Application for practical synthesis of [small alpha]-amino acids

26-Jun-2018 | Ryosuke Takeda; Akie Kawamura; Aki Kawashima; Tatsunori Sato; Hiroki Moriwaki; Kunisuke Izawa; Hidenori Abe; Vadim A ..., Organic & Biomolecular Chemistry, 2018

We report a discovery of new rimantadine [1-(1-adamantyl)ethanamine]-derived chiral ligand and its application for preparation of α-amino acids using second-order asymmetric transformation apporach. The operational ease of experimental procedures coupled with excellent chemical yields and ...


Progress in the synthesis of fluorinated phosphatidylcholines for biological applications

26-Jun-2018 | Marie-Claude Gagnon; Michèle Auger; Jean-François Paquin, Organic & Biomolecular Chemistry, 2018

The synthesis and biophysical studies of fluorinated phospholipids have attracted a lot of interest over the past 40 years. Mono- and polyfluorinated phospholipids, containing 1–4 fluorine atoms, are designed mostly with the goal of developing new model membranes. The fluorine atoms are herein ...


A macrocyclic receptor containing two viologen species connected by conjugated terphenyl groups

26-Jun-2018 | Long Chen; Kate Lim; Tahkur Singh Babra; james o taylor; Martin Pižl; Rob Evans; ann M Chippindale; Frantisek Hartl; ..., Organic & Biomolecular Chemistry, 2018

A macrocyclic receptor molecule containing two viologen species connected by conjugated terphenyl groups has been designed and synthesised. The single-crystal X-ray structure shows that the two viologen residues have a transannular N…N separation of ca. 7.4 Å. Thus, the internal cavity dimensions ...


Total synthesis and structural revision of (±)-nidemone

26-Jun-2018 | Day-Shin Hsu; Chang-Yan Liou, Organic & Biomolecular Chemistry, 2018

Total synthesis of the revised structure of (±)-nidemone has been accomplished from 6-bromo-2-hydroxybenzaldehyde (5) in either six or eight synthetic steps in 6% and 10% overall yield, respectively, without using any protecting group. The revised structure of nidemone was confirmed by ...


Dibenzofuran-4,6-bis(oxazoline) (DBFOX). A Novel trans-Chelating Bis(oxazoline) Ligand for Asymmetric Reactions

26-Jun-2018 | Kennosuke Itoh; Mukund P. Sibi, Organic & Biomolecular Chemistry, 2018

The trans-chelating bis(oxazoline) ligand (R,R)-4,6-dibenzofurandiyl-2,2’-bis(4-phenyloxazoline) [(R,R)-DBFOX/Ph] coordinates metal ions to give C2-symmetric complexes which effectively catalyze a variety of asymmetric reactions. (R,R)-DBFOX/Ph•Ni(ClO4)2•3H2O, whose crystal structure is ...


(2-Fluoroallyl)boronates: new reagents for diastereoselective 2-fluoroallylboration of aldehydes

26-Jun-2018 | Maxim A. Novikov; Oleg M. Nefedov, Organic & Biomolecular Chemistry, 2018

A Pd-catalyzed borylation of 2-fluoroallyl chlorides with B2pin2 in the presence of [(2-MeAll)PdCl]2/TMEDA or [(2-MeAll)Pd(IPr)Cl] was developed to afford (2-fluoroallyl)pinacolboronates with high Z-selectivity. The products proved to be useful for anti-selective 2-fluoroallylboration of aromatic ...


Page 3 From 906
Subscribe to e-mail updates relating to your search

You will receive via e-mail the latest search results matching your search criteria. This service is free of charge and can be cancelled at any time.

Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE