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Relationships among Taste Qualities Assessed with Response-Context Effects

01-Sep-2011 | Wise, P. M., Breslin, P. A. S., Chemical Senses, 2011

Psychophysical judgments often depend on stimulus context. For example, sugar solutions are judged sweeter when a tasteless fruity aroma has been added. Response context also matters; adding a fruity aroma to sugar increases the rated sweetness when only sweetness is considered but not when ...


Differential Inputs from Chemosensory Appendages Mediate Feeding Responses to Glucose in Wild-Type and Glucose-Averse German Cockroaches, Blattella germanica

01-Sep-2011 | Wada-Katsumata, A., Silverman, J., Schal, C., Chemical Senses, 2011

Glucose is a universal phagostimulant in many animal species, including the cockroach Blattella germanica. However, some natural populations of B. germanica have been found that are behaviorally deterred from eating glucose. In dose–response studies, glucose was a powerful phagostimulant for ...


Characterization of Human Fungiform Papillae Cells in Culture

01-Sep-2011 | Ozdener, M. H., Brand, J. G., Spielman, A. I., Lischka, F. W., Teeter, J. H., Breslin, P. A. S., Rawson, N. E., Chemical Senses, 2011

The ability to maintain human fungiform papillae cells in culture for multiple cell cycles would be of considerable utility for characterizing the molecular, regenerative, and functional properties of these unique sensory cells. Here we describe a method for enzymatically isolating human cells ...


The Similarity between Odors and Their Binary Mixtures in Drosophila

01-Sep-2011 | Eschbach, C., Vogt, K., Schmuker, M., Gerber, B., Chemical Senses, 2011

How are odor mixtures perceived? We take a behavioral approach toward this question, using associative odor-recognition experiments in Drosophila. We test how strongly flies avoid a binary mixture after punishment training with one of its constituent elements and how much, in turn, flies avoid an ...


Pretreatment with CP-154526 Blocks the Modifying Effects of Alarm Pheromone on Components of Sexual Behavior in Male, but not in Female, Rats

01-Sep-2011 | Kobayashi, T., Kiyokawa, Y., Takeuchi, Y., Mori, Y., Chemical Senses, 2011

We previously demonstrated that an alarm pheromone released from male donor Wistar rats evoked several physiological and behavioral responses in recipient rats. However, the pheromone effects on social behavior were not analyzed. In the present study, we examined whether the alarm pheromone ...


Oviposition Response of the Moth Lobesia botrana to Sensory Cues from a Host Plant

01-Sep-2011 | Tasin, M., Lucchi, A., Ioriatti, C., Mraihi, M., De Cristofaro, A., Boger, Z., Anfora, G., Chemical Senses, 2011

The grapevine moth Lobesia botrana is a generalist insect herbivore and grapevine is one of its hosts. Previous studies have shown that insects use their olfactory abilities to locate hosts from a distance; whereas contact chemoreception mediates the stimulation of oviposition after landing. ...


Affected by Smells? Environmental Chemical Responsivity Predicts Odor Perception

01-Sep-2011 | Cornell Karnekull, S., Jonsson, F. U., Larsson, M., Olofsson, J. K., Chemical Senses, 2011

Strong negative reactions, physical symptoms, and behavioral disruptions due to environmental odors are common in the adult population. We investigated relationships among such environmental chemosensory responsivity (CR), personality traits, affective states, and odor perception. Study 1 showed ...


Novel Menthol-Derived Cooling Compounds Activate Primary and Second-Order Trigeminal Sensory Neurons and Modulate Lingual Thermosensitivity

01-Sep-2011 | Klein, A. H., Iodi Carstens, M., McCluskey, T. S., Blancher, G., Simons, C. T., Slack, J. P., Furrer, S., Carstens, E., Chemical Senses, 2011

We presently investigated 2 novel menthol derivatives GIV1 and GIV2, which exhibit strong cooling effects. In previous human psychophysical studies, GIV1 delivered in a toothpaste medium elicited a cooling sensation that was longer lasting compared with GIV2 and menthol carboxamide (WS-3). In the ...


Dynamics of Odorant Binding to Thin Aqueous Films of Rat-OBP3

01-Sep-2011 | Yabuki, M., Scott, D. J., Briand, L., Taylor, A. J., Chemical Senses, 2011

Uptake, retention and release of 5 selected odorants (benzaldehyde, 2-methylpyrazine, 2-isobutyl-3-methoxypyrazine, 2-isobutylthiazole, and 2,4,5-trimethylthiazole) by recombinant rat odor-binding protein 3 (rat-OBP3) were measured in a model system under nonequilibrium conditions. Gaseous ...


An impact of CCN2-BMP-2 complex upon chondrocyte biology: evoking a signalling pathway bypasses ERK and Smads?

01-Sep-2011 | Maeda, S., Journal of Biochemistry, 2011

CCN family 2/connective tissue growth factor (CCN2/CTGF) is a secreted protein that regulates diverse cellular functions. In addition to being a growth factor to transmit mitogen-activated protein kinase (MAPK) signalling into cells, through largely unknown mechanism, CCN2 antagonizes bone ...


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