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6,211 Newest Publications about the topic assays

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Nickel nanowires-based composite material applied to the highly enhanced non-enzymatic electro-oxidation of ethanol

01-Jul-2018 | Author(s): Cecilia S. Tettamanti, María L. Ramírez, Fabiana A. Gutierrez, Paula G. Bercoff, Gustavo A. Riv ..., Microchemical Journal, 2018

Publication date: November 2018 Source:Microchemical Journal, Volume 142 Author(s): Cecilia S. Tettamanti, María L. Ramírez, Fabiana A. Gutierrez, Paula G. Bercoff, Gustavo A. Rivas, Marcela C. Rodríguez In this work, we report the building of a nanostructured platform with ...

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Sex reversal following deletion of a single distal enhancer of Sox9

29-Jun-2018 | Nitzan Gonen; Chris R. Futtner; Sophie Wood; S. Alexandra Garcia-Moreno; Isabella M. Salamone; Shiela C. Samson; Ryo ..., Science , 2018

Cell fate decisions require appropriate regulation of key genes. Sox9, a direct target of SRY, is pivotal in mammalian sex determination. In vivo high-throughput chromatin accessibility techniques, transgenic assays, and genome editing revealed several novel gonadal regulatory elements in the ...

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IJMS, Vol. 19, Pages 1904: GW2 Functions as an E3 Ubiquitin Ligase for Rice Expansin-Like 1

28-Jun-2018 | Choi, Beom Seok; Kim, Yeon Jeong; Markkandan, Kesavan ; Koo, Yeon Jong; Song, Jong Tae; Seo, Hak Soo, International Journal of Molecular Sciences, 2018

IJMS, Vol. 19, Pages 1904: GW2 Functions as an E3 Ubiquitin Ligase for Rice Expansin-Like 1 International Journal of Molecular Sciences doi: 10.3390/ijms19071904 Authors: Beom Seok Choi Yeon Jeong Kim Kesavan Markkandan Yeon Jong Koo Jong Tae Song Hak Soo Seo Seed size is ...

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Sensors, Vol. 18, Pages 2038: On the Determination of Uncertainty and Limit of Detection in Label-Free Biosensors

26-Jun-2018 | Lavín, Álvaro ; Vicente, Jesús de; Holgado, Miguel ; Laguna, María F.; Casquel, Rafael ; Santamaría, Beatriz ; Mai ..., Sensors, 2018

Sensors, Vol. 18, Pages 2038: On the Determination of Uncertainty and Limit of Detection in Label-Free Biosensors Sensors doi: 10.3390/s18072038 Authors: Álvaro Lavín Jesús de Vicente Miguel Holgado María F. Laguna Rafael Casquel Beatriz Santamaría María Victoria Maigler Ana ...

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IJMS, Vol. 19, Pages 1877: The RNA Helicase DDX6 Associates with RIG-I to Augment Induction of Antiviral Signaling

26-Jun-2018 | Núñez, Rocío Daviña; Budt, Matthias ; Saenger, Sandra ; Paki, Katharina ; Arnold, Ulrike ; Sadewasser, Anne ; Wolff ..., International Journal of Molecular Sciences, 2018

IJMS, Vol. 19, Pages 1877: The RNA Helicase DDX6 Associates with RIG-I to Augment Induction of Antiviral Signaling International Journal of Molecular Sciences doi: 10.3390/ijms19071877 Authors: Rocío Daviña Núñez Matthias Budt Sandra Saenger Katharina Paki Ulrike Arnold Anne ...

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Going on offense against the gram-negative defense [Microbiology]

26-Jun-2018 | Bryon S. Drown; Paul J. Hergenrother, Proceedings of the National Academy of Sciences current issue, 2018

Bacterial infections resistant to antibiotics are becoming more common, posing a significant health risk (1). The CDC and WHO have identified gram-negative drug-resistant pathogens as being particularly dangerous, and such infections are resistant to nearly all available antibiotics in some cases ...

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Molecules, Vol. 23, Pages 1544: Insights into Structure-Activity Relationships of 3-Arylhydrazonoindolin-2-One Derivatives for Their Multitarget Activity on β-Amyloid Aggregation and Neurotoxicity

26-Jun-2018 | Purgatorio, Rosa ; de Candia, Modesto ; De Palma, Annalisa ; De Santis, Francesco ; Pisani, Leonardo ; Campagna, Fra ..., Molecules, 2018

Molecules, Vol. 23, Pages 1544: Insights into Structure-Activity Relationships of 3-Arylhydrazonoindolin-2-One Derivatives for Their Multitarget Activity on β-Amyloid Aggregation and Neurotoxicity Molecules doi: 10.3390/molecules23071544 Authors: Rosa Purgatorio Modesto de ...

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Combinatorial drug discovery in nanoliter droplets [Engineering]

26-Jun-2018 | Anthony Kulesa; Jared Kehe; Juan E. Hurtado; Prianca Tawde; Paul C. Blainey, Proceedings of the National Academy of Sciences current issue, 2018

The conventional single-agent approach to therapeutics is challenged by the redundancy and feedback in biological networks. The use of multiple drugs in combination might improve desired functional outcomes while reducing toxicity and overcoming drug resistance. However, the complexity and ...

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Cell-based screen for discovering lipopolysaccharide biogenesis inhibitors [Microbiology]

26-Jun-2018 | Ge Zhang; Vadim Baidin; Karanbir S. Pahil; Eileen Moison; David Tomasek; Nitya S. Ramadoss; Arnab K. Chatterjee; Cas ..., Proceedings of the National Academy of Sciences current issue, 2018

The outer membrane of gram-negative bacteria contains LPS on the cell surface. The presence of LPS creates an effective permeability barrier that protects gram-negative bacteria from small hydrophobic molecules. Because the entire LPS biogenesis pathway, including biosynthesis and transport, is ...

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IJMS, Vol. 19, Pages 1879: Ethanolic Extracts from Azadirachta indica Leaves Modulate Transcriptional Levels of Hormone Receptor Variant in Breast Cancer Cell Lines

26-Jun-2018 | Braga, Deisi L.; Mota, Sara T. S.; Zóia, Mariana A. P.; Lima, Paula M. A. P.; Orsolin, Priscila C.; Vecchi, Lar ..., International Journal of Molecular Sciences, 2018

IJMS, Vol. 19, Pages 1879: Ethanolic Extracts from Azadirachta indica Leaves Modulate Transcriptional Levels of Hormone Receptor Variant in Breast Cancer Cell Lines International Journal of Molecular Sciences doi: 10.3390/ijms19071879 Authors: Deisi L. Braga Sara T. S. Mota Mariana A. ...

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