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1,151 Newest Publications about the topic mass spectrometers

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Multi-element ion-exchange chromatography and high-precision MC-ICP-MS isotope analysis of Mg and Ti from sub-mm-sized meteorite inclusions

28-May-2018 | K. K. Larsen; D. Wielandt; M. Bizzarro, Journal of Analytical Atomic Spectrometry, 2018

The analytical improvement of new generation mass spectrometers has reached a level required for high-precision isotope analysis of very small and unique natural samples. The multi-element isotopic signatures of meteorite inclusions can potentially provide detailed insight into the origin of our ...

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IMTBX and Grppr: Software for Top-Down Proteomics Utilizing Ion Mobility-Mass Spectrometry

16-Jan-2018 | Dmitry M. Avtonomov; Daniel A. Polasky; Brandon T. Ruotolo; Alexey I. Nesvizhskii, Analytical Chemistry, 2018

Top-down proteomics has emerged as a transformative method for the analysis of protein sequence and post-translational modifications (PTMs). Top-down experiments have historically been performed primarily on ultrahigh resolution mass spectrometers due to the complexity of spectra resulting from ...

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Ion traps in modern mass spectrometry

30-Oct-2017 | Dirk Nolting, Robert Malek, Alexander Makarov, Mass Spectrometry Reviews, 2017

This review is devoted to trapping mass spectrometry wherein ions are confined by electromagnetic fields for prolonged periods of time within limited volume, with mass measurement taking place within the same volume. Three major types of trapping mass spectrometers are discussed, specifically ...

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Nontarget Screening with High Resolution Mass Spectrometry in the Environment: Ready to Go?

26-Sep-2017 | Juliane Hollender; Emma L. Schymanski; Heinz P. Singer; P. Lee Ferguson, Environmental Science & Technology, 2017

The vast, diverse universe of organic pollutants is a formidable challenge for environmental sciences, engineering, and regulation. Nontarget screening (NTS) based on high resolution mass spectrometry (HRMS) has enormous potential to help characterize this universe, but is it ready to go for real ...

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Expanding Single Particle Mass Spectrometer Analyses for the Identification of Microbe Signatures in Sea Spray Aerosol

22-Sep-2017 | Camille M. Sultana; Hashim Al-Mashat; Kimberly A. Prather, Analytical Chemistry, 2017

Ocean-derived microbes in sea spray aersosol (SSA) have the potential to influence climate and weather by acting as ice nucleating particles in clouds. Single particle mass spectrometers (SPMSs), which generate in situ single particle composition data, are excellent tools for characterizing ...

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Expanding Single Particle Mass Spectrometer Analyses for the Identification of Microbe Signatures in Sea Spray Aerosol

22-Sep-2017 | Camille M. Sultana; Hashim Al-Mashat; Kimberly A. Prather, Analytical Chemistry, 2017

Ocean-derived microbes in sea spray aersosol (SSA) have the potential to influence climate and weather by acting as ice nucleating particles in clouds. Single particle mass spectrometers (SPMSs), which generate in situ single particle composition data, are excellent tools for characterizing ...

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Comparison of linear intrascan and interscan dynamic ranges of Orbitrap and ion‐mobility time‐of‐flight mass spectrometers

06-Sep-2017 | Anton Kaufmann, Stephan Walker, Rapid Communications in Mass Spectrometry, 2017

Abstract Rationale The linear intrascan and interscan dynamic ranges of mass spectrometers are important in metabolome and residue analysis. A large linear dynamic range is mandatory if both low and high abundance ions have to be detected and quantitated in heavy matrix samples. These ...

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AssayR: A Simple Mass Spectrometry Software Tool for Targeted Metabolic and Stable Isotope Tracer Analyses

05-Sep-2017 | Jimi Wills; Joy Edwards-Hicks; Andrew J. Finch, Analytical Chemistry, 2017

Metabolic analyses generally fall into two classes: unbiased metabolomic analyses and analyses that are targeted toward specific metabolites. Both techniques have been revolutionized by the advent of mass spectrometers with detectors that afford high mass accuracy and resolution, such as ...

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Resolution Ladder for High-Resolution Mass Spectrometry

01-Sep-2017 | Matthias Schittmayer; Ruth Birner-Gruenberger, Analytical Chemistry, 2017

High-resolution mass spectrometry has become a key technology in life sciences. Since it is often unfeasible to find pairs of analytes with an appropriate mass difference to actually quantify the resolution experimentally, resolution is usually calculated from the shape of a single mass peak. In ...

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Derivatization agents for electrochemical detection in amino acid, peptide and protein separations: the hidden electrochemistry?

25-Jul-2017 | Tania Sierra, Agustin G. Crevillen, Alberto Escarpa, ELECTROPHORESIS, 2017

In proteomics and clinical analysis, LIF and MS are the most used detectors coupled to separation techniques. MS offers good sensitivity and analyte identification ability but, as counterbalance, it is expensive and it needed background electrolytes compatible with mass spectrometers. LIF ...

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