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1,438 Newest Publications about the topic nucleic acids

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Highly sensitive detection of nucleic acids using cascade amplification strategy based on exonuclease III-assisted target recycling and conjugated polyelectrolytes

20-Jun-2018 | Biqing Bao; Yanrui Pan; Binbin Gu; Jia Chen; Yu Xu; Peng Su; Yunfei Liu; Li Tong; Lian-Hui Wang, Analyst, 2018

In this paper, a novel ratiometric and cascade amplification strategy was developed by combing the unique signal amplification and effecitive fluorescence resonance energy transfer (FRET) property of conjugated polymers with Exo III-assisted target recycling method. The target DNA (ssDNAc) could ...

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Ultrasensitive Detection of Nucleic Acids Based on Dually Enhanced Fluorescence Polarization

12-Jun-2018 | Bin Wang; Dahai Ren; Zheng You; Yaxiaer Yalikun; Yo Tanaka, Analyst, 2018

Highly sensitive detection of nucleic acids is crucial for genomics, transcriptomics, and heterogeneity studies. Conventional fluorescence polarization and intensity-based assays for DNA/RNA measurements often suffer from a poor limit of detection and a long test period. A versatile nanoscale ...

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Human plasma and serum extracellular small RNA reference profiles and their clinical utility [Medical Sciences]

05-Jun-2018 | Klaas E. A. Max; Karl Bertram; Kemal Marc Akat; Kimberly A. Bogardus; Jenny Li; Pavel Morozov; Iddo Z. Ben-Dov; Xin ..., Proceedings of the National Academy of Sciences current issue, 2018

Nucleic acids mediate storage and expression of genetic information. Extracellular DNA (exDNA) and exRNA are traces of nucleic acids released from cells into the extracellular environment. Their use as disease biomarkers has been limited by technical challenges in their isolation caused by ...

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Focusing manipulation of microalgae in a microfluidic device using self-produced macromolecules

01-Jun-2018 | Min Jung Kim; Jae Ryoun Youn; Young Seok Song, Lab on a Chip, 2018

Extracellular polymeric substances (EPSs) are self-produced biosynthetic macromolecules that have a three-dimensional architecture in bacterial biofilms and are mainly composed of a mixture of polysaccharides, proteins and nucleic acids. Compared with synthetic polymers, EPSs can have a long ...

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Focusing manipulation of microalgae in a microfluidic device using self-produced macromolecules

01-Jun-2018 | Min Jung Kim; Jae Ryoun Youn; Young Seok Song, Lab on a Chip, 2018

Extracellular polymeric substances (EPSs) are self-produced biosynthetic macromolecules that have a three-dimensional architecture in bacterial biofilms and are mainly composed of a mixture of polysaccharides, proteins and nucleic acids. Compared with synthetic polymers, EPSs can have a long ...

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Engineered photoproteins that give rise to photosynthetically-incompetent bacteria are effective as photovoltaic materials for biohybrid photoelectrochemical cells

01-Jun-2018 | Juntai Liu; Vincent M. Friebe; David J. K. Swainsbury; Lucy I. Crouch; David A. Szabo; Raoul N. Frese; Michael ..., Faraday Discussions, 2018

Reaction centre/light harvesting proteins such as the RCLH1X complex from Rhodobacter sphaeroides carry out highly quantum-efficient conversion of solar energy through ultrafast energy transfer and charge separation, and these pigment-proteins have been incorporated into biohybrid ...

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Engineered photoproteins that give rise to photosynthetically-incompetent bacteria are effective as photovoltaic materials for biohybrid photoelectrochemical cells

01-Jun-2018 | Juntai Liu; Vincent M. Friebe; David J. K. Swainsbury; Lucy I. Crouch; David A. Szabo; Raoul N. Frese; Michael ..., Faraday Discussions, 2018

Reaction centre/light harvesting proteins such as the RCLH1X complex from Rhodobacter sphaeroides carry out highly quantum-efficient conversion of solar energy through ultrafast energy transfer and charge separation, and these pigment-proteins have been incorporated into biohybrid ...

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Direct surface-enhanced Raman scattering (SERS) spectroscopy of nucleic acids: from fundamental studies to real-life applications

01-Jun-2018 | Eduardo Garcia-Rico; Ramon A. Alvarez-Puebla; Luca Guerrini, Chemical Society Reviews, 2018

Plasmonic optical biosensors for the analysis of nucleic acids have drawn a great deal of interest in nanomedicine because of their capability to overcome major limitations of conventional methods. Within this realm, surface-enhanced Raman scattering (SERS)-based sensing is progressively emerging ...

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Fluorescent excimers and exciplexes of the purine base derivative 8-phenylethynyl-guanine in DNA hairpins

01-Jun-2018 | Kristen E. Brown; Arunoday P. N. Singh; Yi-Lin Wu; Lin Ma; Ashutosh K. Mishra; Brian T. Phelan; Ryan M. Young; ..., Faraday Discussions, 2018

The ground- and excited-state electronic interactions between the nucleobase analog 8-(4′-phenylethynyl)deoxyguanosine, EG, with natural nucleobases and 7-deazaguanine, as well as between adjacent EG base analogs, have been characterized using a combination of steady-state spectroscopy and ...

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Fluorescent excimers and exciplexes of the purine base derivative 8-phenylethynyl-guanine in DNA hairpins

01-Jun-2018 | Kristen E. Brown; Arunoday P. N. Singh; Yi-Lin Wu; Lin Ma; Ashutosh K. Mishra; Brian T. Phelan; Ryan M. Young; ..., Faraday Discussions, 2018

The ground- and excited-state electronic interactions between the nucleobase analog 8-(4′-phenylethynyl)deoxyguanosine, EG, with natural nucleobases and 7-deazaguanine, as well as between adjacent EG base analogs, have been characterized using a combination of steady-state spectroscopy and ...

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