UMass Amherst researcher receives $1.8 million to create Center for Autonomous Chemistry

24-Aug-2017 - USA

University of Massachusetts Amherst chemist Sankaran "Thai" Thayumanavan has received a three-year, $1.8 million grant from the National Science Foundation to create a multi-university Center for Autonomous Chemistry, where he and colleagues, including chemist Vince Rotello, will seek to design artificial self-activating systems, or "automatic control as nature does it," in Thayumanavan's words.

The center will also include one researcher each from partner institutions MIT, the University of Michigan and the University of Illinois at Urbana-Champaign. The Phase 1 funding comes as part of NSF's Center for Chemical Innovation program.

Vice Chancellor for Research and Engagement Michael Malone says, "Autonomous chemistry is a terrific new area for both basic research and ultimately high-impact applications. We are very excited to see Professor Thayumanavan and his excellent collaborators receive this NSF funding."

Thayumanavan says, "We'll be looking to nature for mechanisms and techniques, looking into biomimicry, to try to understand how biological systems accomplish autonomous responses to subtle changes in their environment."

For example, many components of the immune system are quiet and dormant until an irritant or pathogen is detected, he says. "But once that happens, it's activated. It's automatic, organically driven, and that is what we refer to as autonomous. The response requires no other intervention."

Further, "If you look for artificial systems with that kind of capability, you really don't find any. But it would be really valuable if we could develop something like it. We want to figure out the ways nature uses molecular interactions to create autonomous function."

Thayumanavan believes that a broad range of applications exist for autonomous chemistry but at the moment personalized medicine has a high profile and the need is also readily understood.

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