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Chemical name 2,5-Dimethoxy-4-methyl-phenethylamine or
Chemical formula C11H17NO2
Molecular mass 195.26 g/mol
Melting point 213 - 214 °C (hydrochloride)
CAS number 24333-19-5
Legal status Class A (UK)

2C-D is a psychedelic drug of the 2C family. It was first synthesized by Alexander Shulgin, sometimes used as an entheogen. The full name of the chemical is 2,5-dimethoxy-4-methyl-phenethylamine. In his book PiHKAL (Phenethylamines I Have Known and Loved), Shulgin lists the dosage range as being from 20 to 60 mg and many people recommend even high doses. Lower doses (generally 10mg or less) of 2C-D have been explored as a potential nootropic, albeit with mixed results. 2C-D is generally taken orally, though may be insufflated (ie taken nasally). Insufflating tends to cause intense pain, however, and the dosage level is usual much lower, typically in the region of 1 to 15mg.

Not much information is known about the toxicity of 2C-D, as no major studies have been conducted. According to Shulgin, the effects of 2C-D typically last for 4-6 hours. Shulgin himself referred to this substance as a “pharmacological tofu,” meaning that when mixed with other substances, it can extend or potentiate their effects without coloring the experience too much, in a manner similar to how tofu absorbs the flavors of sauces or spices it is cooked with. Some people have claimed 2C-D is relatively uninteresting on its own, but many other users have strongly disagreed with this assessment and believe instead 2C-D to be a true psychedelic in its own right. Hanscarl Leuner, working in Germany, explored the use of 2C-D under the name LE-25 in psychotherapeutic research.


2C-D is currently unscheduled and uncontrolled in the United States, but the possession and sale of 2C-D could potentially be prosecuted under the Federal Analog Act due to its structural similarities to 2C-B and 2C-T-7.

2C-D and all other compounds featuring in PiHKAL are illegal drugs in the United Kingdom.


This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "2C-D". A list of authors is available in Wikipedia.
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