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Bendectin, (known as Debendox® in the UK) is a mixture of pyridoxine (Vitamin B-6), and doxylamine, is a drug prescribed to treat nausea and vomiting associated with morning sickness. It was voluntarily removed from the market in 1983 by its manufacturer, Merrell Dow Pharmaceuticals, following numerous lawsuits alleging that it caused birth defects. These lawsuits were largely unfounded, however, as the rate of birth defects in the general population did not increase prior to drug release or decrease following its removal. In the general population about 3% of babies are born with congenital defects. There was an overwhelming body of evidence at the time and which continues accumulating to this day that Bendectin does not cause birth defects. The most famous case involving the drug is Daubert v. Merrell Dow Pharmaceuticals (1993), which left lasting implications for the way science is used in the courtroom. The Supreme Court ruled that judges had the responsibility to keep junk science out of the courtroom.
Additional recommended knowledge
The drug has recently resurfaced and is currently marketed under the same name.
Daubert v. Merrell Dow Pharmaceuticals
Categories: Antiemetics | Withdrawn drugs
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Bendectin". A list of authors is available in Wikipedia.|