My watch list
With an accout for my.chemeurope.com you can always see everything at a glance – and you can configure your own website and individual newsletter.
- My watch list
- My saved searches
- My saved topics
- My newsletter
Bernthsen acridine synthesis
The Bernthsen acridine synthesis is the chemical reaction of a diarylamine heated with a carboxylic acid (or acid anhydride) and zinc chloride to form a 9-substituted acridine.
Additional recommended knowledge
Using zinc chloride, one must heat the reaction to 200-270 °C for 24hrs. The use of polyphosphoric acid will give acridine products at a lower temperature, but also with decreased yields.
- ^ Bernthsen, A.; Ann. 1878, 192, 1.
- ^ Bernthsen, A.; Ann. 1884, 224, 1.
- ^ Popp, F. D. J. Org. Chem. 1962, 27, 2658. (doi:10.1021/jo01054a518)
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Bernthsen_acridine_synthesis". A list of authors is available in Wikipedia.
Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE