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Blow fill seal

Blow fill seal technology was originally developed in Europe in the 1930's and was introduced in the United States in the 1960's, but has just recently become more prevalent as it is now considered the superior form of aseptic processing by the Food and Drug Administration (FDA) in the packaging of pharmaceutical and healthcare products.

The concept of aseptic blow fill seal (BFS) is that a container is formed, filled, and sealed in a continuous process without human intervention in a sterile enclosed area inside a machine. The process is multi-stepped, pharmaceutical grade resin is extruded into a tube, which is then formed into a container. A mandrel is inserted into the newly formed container and filled. The container is then sealed, all inside a sterile shrouded chamber inside the machine. The product is then discharged to a non-sterile area for packaging and distribution.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Blow_fill_seal". A list of authors is available in Wikipedia.
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