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Chemosensory protein

Chemosensory proteins are a class of small (10-15 kDa), soluble proteins characterised for the first time by Angeli et al. (1999) as secreted into the sensillar lymph of insect chemosensory sensilla. Some members of CSPs were already discovered in Drosophila, and other insects, although not clear link with olfactory or gustatory function was assigned. In the last years CSPs were found in insect contact and olfactory sensilla, but other members showed peculiar functions. In Apis mellifera one member was found to be involve in larva developments and in Blatta a CSP is involved in leg regeneration. Binding activity of volatile compounds has been described in a similar way as in other group of soluble sensillar proteins, called Odorant binding proteins or OBPs. CSPs do not share sequence similarity with OBPs and are characterized by only 4 conserved cysteines, where insect OBPs have 6 conserved cysteines.


- Angeli S., Ceron F., Scaloni A., Monti M., Monteforti G., Minnocci A., Petacchi R. and Pelosi P. (1999) “Purification, structural characterisation, cloning and immunocytochemical localisation of chemoreception proteins from Schistocerca gregaria” European Journal of Biochemistry 292, 745-754 PMID: 10411636

- Tomaselli S., Crescenzi O., Sanfelice D., Ab E., Wechselberger R., Angeli S., Scaloni A., Boelens R., Tancredi T., Pelosi P., Picone D. (2006) Solution structure of a chemosensory protein from the desert locust Schistocerca gregaria. Biochemistry. 45(35):10606-13 PMID: 16939212

- Mosbah A., Campanacci V., Lartigue A., Tegoni M., Cambillau C. and Darbon, H. (2003) Solution structure of a chemosensory protein from the moth Mamestra brassicae, Biochem. J. 369, 39-44. PMID: 12217077

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Chemosensory_protein". A list of authors is available in Wikipedia.
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