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Combination of
Amiloride Potassium-sparing diuretic
Frusemide Loop diuretic
CAS number  ?
ATC code C03EB01
PubChem  ?
Therapeutic considerations
Pregnancy cat.


Legal status


Routes Oral

Co-amilofruse (BAN) is a non-proprietary name used to denote a combination of amiloride and the formerly named frusemide (now the INN termed furosemide). Co-amilofruse in the treatment of fluid retension (oedema), either in the legs (peripheral edema) or on the lungs (pulmonary oedema). The stronger furosemide loop diuretic has a tendency to cause low potassium levels (hypokalaemia) that may be prevented by the potassium-sparing effects of amiloride.


Two strengths of co-amilofruse are available:

  • 2.5 mg amiloride with 20 mg furosemide, BAN of Co-amilofruse 2.5/20 (brand name Frumil LS)
  • 5 mg amiloride with 40 mg furosemide, BAN of Co-amilofruse 5/4-0 (brand name Frumil)


This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Co-amilofruse". A list of authors is available in Wikipedia.
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