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In chemistry a convergent synthesis is a strategy that aims to improve the efficiency of multi-step chemical synthesis. In linear synthesis the overall yield quickly drops with each reaction step:
Additional recommended knowledge
Suppose the yield is 50% for each reaction, the overall yield of D is only 12.5% from A.
In a convergent synthesis
the overall yield of E (25%) looks much better. Convergent synthesis is applied in the synthesis of complex molecules (see total synthesis) and involve fragment coupling and independent synthesis.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Convergent_synthesis". A list of authors is available in Wikipedia.|