My watch list
my.chemeurope.com  

my.chemeurope.com

With an accout for my.chemeurope.com you can always see everything at a glance – and you can configure your own website and individual newsletter.

  • My watch list
  • My saved searches
  • My saved topics
  • My newsletter
Register free of charge
Login  
eng  
DeutschEnglishFrançaisEspañol

Decitabine



Decitabine
Systematic (IUPAC) name
4-amino-1-(2-deoxy-b-D-erythro-pentofuranosyl)-
1,3,5-triazin-2(1H)-one
Identifiers
CAS number 2353-33-5
ATC code  ?
PubChem 451668
Chemical data
Formula C8H12N4O4 
Mol. mass 228.0859 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding <1%
Metabolism  ?
Half life 30 minutes
Excretion  ?
Therapeutic considerations
Pregnancy cat.

D

Legal status
Routes Intravenous

Decitabine (trade name Dacogen), or 5-aza-2'-deoxycytidine, is indicated for treatment of patients with myelodysplastic syndrome (MDS), including previously treated and untreated, de novo, and secondary MDS of all FAB subtypes and Intermediate-1, Intermediate-2, and High-Risk IPSS groups. It functions in the same way as 5-Azacytidine.

Basic information

  • Trade Name: Dacogen
  • Generic Name: decitabine
  • FDA approved: May 2, 2006
  • Classification: demethylating agent
  • Manufacturer: MGI Pharma
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Decitabine". A list of authors is available in Wikipedia.
Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE