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The major metabolites formed from most drug metabolism are detoxication products. There are two common patterns observed:

  1. A drug with potent pharmacological activity is converted to a major metabolite with markedly reduced or no pharmacological activity (e.g., Pentobarbital and Hydroxypentobarbital)
  2. A drug is converted to a metabolite with roughly equivalent or slightly lower pharmacological activity.
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Detoxication". A list of authors is available in Wikipedia.
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