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Systematic (IUPAC) name
1-[2-[4-(3-trifluoromethyl phenyl) piperazin-1-yl] ethyl] benzimidazol- [1H]-2-one
CAS number 167933-07-5
ATC code  ?
PubChem  ?
Chemical data
Formula C20H21F3N4O 
Mol. mass 390.40 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.


Legal status
Routes  ?

Flibanserin[1] is a drug produced by Boehringer Ingelheim. It is currently being investigated as a drug for women suffering from decreased sexual desire. It is a 5-HT1A serotonin receptor agonist and 5-HT2a serotonin receptor antagonist that had initially been developed as an anti-depressant.[2]


  1. ^ Borsini F, Evans K, Jason K, Rohde F, Alexander B, Pollentier S (summer 2002). "Pharmacology of flibanserin". CNS Drug Rev. 8 (2): 117-142.
  2. ^ Invernizzi RW, Sacchetti G, Parini S, Acconcia S, Samanin R (Aug 2003). "Flibanserin, a potential antidepressant drug, lowers 5-HT and raises dopamine and noradrenaline in the rat prefrontal cortex dialysate: role of 5-HT(1A) receptors.". Br J Pharmacol. 139 (7): 1281-8.

  • Viagra for women?.
  • Region-dependent effects of flibanserin and buspirone on adenylyl cyclase activity in the human brain
  • Flibanserin has anxiolytic effects without locomotor side effects in the infant rat ultrasonic vocalization model of anxiety
  • Effect of flibanserin (BIMT 17), fluoxetine, 8-OH-DPAT and buspirone on serotonin synthesis in rat brain

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Flibanserin". A list of authors is available in Wikipedia.
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