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Gadodiamide



Gadodiamide
Systematic (IUPAC) name
2-[bis[2-(carboxylatomethyl-(methylcarbamoylmethyl)amino)ethyl]amino]acetate; gadolinium(+3) cation
Identifiers
CAS number 122795-43-1
ATC code  ?
PubChem 60754
Chemical data
Formula C16H28GdN5O9 
Mol. mass 591.672g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding negligible
Metabolism not metabolized
Half life 77.8 minutes
Excretion renal
Therapeutic considerations
Pregnancy cat.

C(US)

Legal status

℞-only(US)

Routes i.v.

Gadodiamide is a gadolinium based contrast agent used in MR imaging procedures to assist in the visualization of blood vessels. It is commonly marketed under the trade name Omniscan.

Uses

Gadodiamide is used to visualize blood vessels during MRI procedures. The use of gadodiamide in these scans allows for the diagnosis of intracranial lesions or blood-brain barrier anomalies.[1] It is a high osmolarity contrast agent at 789 mOsmol per kg of water.

Gadolinium based agents may cause a toxic reaction known as NSF in patients with severe kidney problems.

References

  1. ^ Gadodiamide Drug Information. Drugs.com Professional. Micromedex (9 January 2007). Retrieved on 2007-2-19.
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Gadodiamide". A list of authors is available in Wikipedia.
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