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Group III intron
Group III intron is a class of introns found in mRNA genes of chloroplasts in euglenoid protists. They have a conventional group II-type dVI with a bulged adenosine, a streamlined dI, no dII-dV, and a relaxed splice site consensus. Splicing is by two transesterification reactions with a dVI bulged adenosine as initiating nucleophile; the intron is exercised as a lariat.
Additional recommended knowledge
Discovery and identification
Montandon,P. and Stutz,E. (1984) and Hallick,R.B. et al. (1988 and 1989) reported examples of a novel type of introns in Euglena chloroplast. In 1989, David A.Christopherl and Richard B.Hallickl proposed the title, Group III introns to identify this new class with the following characteristics:
In 1994, discovery of a group III intron with a length of one order of magnitude longer indicated that length alone is not the determinant of splicing in Group III introns.
Splicing of group III introns occurs through lariat and circular RNA formation. Similarities between group III and nuclear introns include conserved 5' boundary sequences, lariat formation, lack of internal structure, and ability to use alternate splice boundaries.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Group_III_intron". A list of authors is available in Wikipedia.|