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Hippocalcin



hippocalcin
Identifiers
Symbol HPCA
Entrez 3208
HUGO 5144
OMIM 142622
RefSeq NM_002143
UniProt P84074
Other data
Locus Chr. 1 p35-p34.2

Hippocalcin is a calcium-binding protein that belongs to neuronal calcium sensor (NCS) family of proteins. It expressed in mammalian brains especially in the hippocampus. It possesses a Ca2+/myristoyl switch.

Additional recommended knowledge

It takes part in the following prosesses:

  • Activation of PLD and PLD2 expression
  • Involved in long term depression in hippocampal neuron
  • Required for normal spatial learning


It interacts with following proteins:

  • Neuronal apoptosis inhibitory protein (NAIP)
  • Mixed lineage kinase 2 (MLK2)MLK2 is myosin light chain kinase 2
  • The b2 adaptin of the AP2 complex
  • Calcium-dependent activator protein for secretion (CAPS)
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Hippocalcin". A list of authors is available in Wikipedia.
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