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Additional recommended knowledge
The usual scenario involving a hypothetical protein is in gene identification during genome analysis. When the bioinformatic tool used for the gene identification finds a large open reading frame without an analog in the protein database, it returns "hypothetical protein" as an annotation remark.
The function of a hypothetical protein can also be predicted by domain homology searches with various confidence levels.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Hypothetical_protein". A list of authors is available in Wikipedia.|