MLL1 or mixed-lineage leukemia 1 is a histone methyltransferase deemed a positive global regulator of gene transcription. This protein belongs to the group of histone-modifying enzymes and is involved in the epigenetic maintenance of transcriptional memory and the pathogenesis of human leukemias. It also may participate in the process of GAD67 downregulation in schizophrenia.
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