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Systematic (IUPAC) name
CAS number 119797-12-5
ATC code V08CA05
PubChem 107732
Chemical data
Formula C22H28MnN4O14P2 
Mol. mass 689.362 g/mol
Pharmacokinetic data
Bioavailability NA
Protein binding 27% (manganese)
Negligible (DPDP)
Metabolism  ?
Half life 20 minutes (manganese)
50 minutes (DPDP)
Excretion Renal and fecal (manganese)
Renal (DPDP)
Therapeutic considerations
Pregnancy cat.

Not to be used

Legal status
Routes Intravenous infusion

Mangafodipir (sold under the brand name Teslascan as mangafodipir trisodium) is a contrast agent delivered intravenously to enhance contrast in magnetic resonance imaging (MRI) of the liver. It has two parts, paramagnetic manganese (II) ions and the chelating agent fodipir (dipyridoxyl diphosphate, DPDP). Normal liver tissue absorbs the manganese more than abnormal or cancerous tissue. The manganese shortens the longitudinal relaxation time (T1), making the normal tissue appear brighter in MRIs. This enhanced contrast allows lesions to be more easily identified.


  • MedlinePlus data sheet
  • Medsafe data sheet
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Mangafodipir". A list of authors is available in Wikipedia.
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