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Metaxalone



Metaxalone
Systematic (IUPAC) name
5-[(3,5-dimethylphenoxy)methyl]oxazolidin-2-one
Identifiers
CAS number 1665-48-1
ATC code  ?
PubChem 15459
DrugBank APRD00514
Chemical data
Formula C12H15NO3 
Mol. mass 221.252 g/mol
Pharmacokinetic data
Bioavailability Unknown
Metabolism Hepatic
Half life 9.2 (± 4.8) hours
Excretion Renal
Therapeutic considerations
Pregnancy cat.

C(US)

Legal status

-only(US)

Routes Oral

Metaxalone (marketed by King Pharmaceuticals under the brand name Skelaxin®) is a muscle relaxant used to relax muscles and relieve pain caused by strains, sprains, and other musculoskeletal conditions. Its exact mechanism of action is not known, but it may be due to general central nervous system depression. It is considered to be a moderately strong muscle relaxant, with relatively low incidence of side effects. Skelaxin comes in an 800 mg scored tablet. It previously came in both 400 mg and 800 mg tablets. The 400 mg tablet has been discontinued. Possible side effects include nausea, vomiting, drowsiness and CNS side effects such as dizziness, headache, and irritability.

Additional recommended knowledge


 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Metaxalone". A list of authors is available in Wikipedia.
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