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Oxacillin



Oxacillin
Systematic (IUPAC) name
(2R,5R,6S)-3,3-dimethyl-6-[(5-methyl-3-phenyl-
1,2-oxazole-4-carbonyl)amino]-7-oxo-4-thia-1-
azabicyclo[3.2.0]heptane-2-carboxylic acid
Identifiers
CAS number 66-79-5
ATC code J01CF01 J01CF04
PubChem 6196
Chemical data
Formula C19H19N3O5S 
Mol. mass 401.437 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status
Routes  ?

Oxacillin sodium (trade name Bactocill) is a narrow spectrum beta-lactam antibiotic of the penicillin class. It has been used particularly in the treatment of Staphylococcus aureus infection, and resistant strains may be called oxacillin-resistant Staphylococcus aureus (ORSA). It is not in use in the UK (which only uses it for laboratory identification of MRSA and to detect penicillin resistance in Streptococcus pneumoniae).

Additional recommended knowledge

Is very active against gram negative organisms such as E.coli (possibly incorrect stetement. need to verify).

 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Oxacillin". A list of authors is available in Wikipedia.
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