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Systematic (IUPAC) name
CAS number 634-03-7
ATC code  ?
PubChem 12460
Chemical data
Formula C12H17NO 
Mol. mass 191.27
Pharmacokinetic data
Bioavailability Peak plasma levels occur within 1 to 3 hours. Absorption is usually complete by 4 to 6 hours
Metabolism hepatic
Half life 19-24 hours
Excretion Urinary elimination
Therapeutic considerations
Pregnancy cat.

C (US)

Legal status


Routes Oral
Indicated for:
  • obesity

Phendimetrazine (Bontril®) is a weight loss medication. Phendimetrazine is chemically related to amphetamines and is a Schedule III drug under the Convention on Psychotropic Substances. In the United States, phendimetrazine is a Schedule III controlled substance under the Uniform Controlled Substances Act of 1970.

Phendimetrazine is used clinically in the form of phendimetrazine tartrate.


Approximately 30% of a given dose of phendimetrazine is metabolized into phenmetrazine, which may account for part of its anorectic effect, and probably also influences abuse potential; individuals who metabolise a greater proportion of phendimetrazine into phenmetrazine are more likely to develop problems with dependence and addiction.

According to the "List of psychotropic substances under international control," phendimetrazine is a Schedule IV controlled substance.[citation needed]

Phendimetrazine is listed as a Schedule III substance under the U.S. Controlled Substance Act in the 2007 Drug Identification Bible, pg 615 and under Section 11056(b)(6) California Health & Safety Code.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Phendimetrazine". A list of authors is available in Wikipedia.
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