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A quinoxaline, also called a benzopyrazine, in organic chemistry, is a heterocyclic compound containing a ring complex made up of a benzene ring and a pyrazine ring. They are isomeric with quinazolines.

Additional recommended knowledge

Quinoxalines are used as dyes, pharmaceuticals and antibiotics such as Echinomycin, Levomycin and Actinoleutin.

They are formed by the condensing ortho-diamines with 1,2-diketone; the parent substance of the group, quinoxaline, resulting when glyoxal is so condensed, whilst substitution derivatives arise when α-ketonic acids, α-chlorketones, α-aldehyde alcohols and α-ketone alcohols are used in place of diketones.

One study used 2-Iodoxybenzoic acid (IBX) as a catalyst in the reaction of benzil with o-phenylenediamine [1]:


  1. ^ Facile synthesis of quinoxaline derivatives using o-iodoxybenzoic acid (IBX) at room temperature (06-2190LP) Majid M. Heravi, Khadijeh Bakhtiari, Maryam H. Tehrani, Negar M. Javadi, and Hossien A. Oskooie ARKIVOC 2006 (xvi) 16-22 provisional link

This article incorporates text from the Encyclopædia Britannica Eleventh Edition, a publication now in the public domain.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Quinoxaline". A list of authors is available in Wikipedia.
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