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A quinoxaline, also called a benzopyrazine, in organic chemistry, is a heterocyclic compound containing a ring complex made up of a benzene ring and a pyrazine ring. They are isomeric with quinazolines.

Quinoxalines are used as dyes, pharmaceuticals and antibiotics such as Echinomycin, Levomycin and Actinoleutin.

They are formed by the condensing ortho-diamines with 1,2-diketone; the parent substance of the group, quinoxaline, resulting when glyoxal is so condensed, whilst substitution derivatives arise when α-ketonic acids, α-chlorketones, α-aldehyde alcohols and α-ketone alcohols are used in place of diketones.

One study used 2-Iodoxybenzoic acid (IBX) as a catalyst in the reaction of benzil with o-phenylenediamine [1]:


  1. ^ Facile synthesis of quinoxaline derivatives using o-iodoxybenzoic acid (IBX) at room temperature (06-2190LP) Majid M. Heravi, Khadijeh Bakhtiari, Maryam H. Tehrani, Negar M. Javadi, and Hossien A. Oskooie ARKIVOC 2006 (xvi) 16-22 provisional link

This article incorporates text from the Encyclopædia Britannica Eleventh Edition, a publication now in the public domain.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Quinoxaline". A list of authors is available in Wikipedia.
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