To use all functions of this page, please activate cookies in your browser.
With an accout for my.chemeurope.com you can always see everything at a glance – and you can configure your own website and individual newsletter.
- My watch list
- My saved searches
- My saved topics
- My newsletter
Small Temporal RNA or stRNA regulate gene expression during worm development by preventing the mRNAs they bind to being translated
Additional recommended knowledge
In contrast to siRNA downregulate expression of target RNAs after translation initiation without affecting mRNA stability.
stRNAs exert negative post-transcriptional regulation by binding to complementary sequences in the 3' untranslated regions of their target genes. stRNAs are transcribed as longer precursor RNAs that are processed by the RNase Dicer/DCR-1 and members of the RDE-1/AGO1 family of proteins, which are better known for their roles in RNA interference (RNAi). stRNAs may function to control temporal identity during development in C. elegans and other organisms
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "StRNA". A list of authors is available in Wikipedia.|