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Sulfadiazine



Sulfadiazine
Systematic (IUPAC) name
4-amino-N-pyrimidin-2-yl-benzenesulfonamide
Identifiers
CAS number 68-35-9
ATC code J01EC02
PubChem 2215
DrugBank APRD00190
Chemical data
Formula C10H10N4O2S 
Mol. mass 250.278 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status

Approved Drug

Routes Cream

Sulfadiazine is a sulfonamide antibiotic. It eliminates bacteria that cause infections by stopping the production of folic acid inside the bacterial cell, and is commonly used to treat urinary tract infections (UTIs).

In combination, sulfadiazine and pyrimethamine, can be used to treat toxoplasmosis, a disease caused by Toxoplasma gondii. This may present in an AIDS patient as multiple ring enhancing lesions on CT. Pregnant women should avoid contact with cat litter which may contain Toxoplasma oocysts.

Side effects reported for sulfadiazine include: nausea, upset stomach, loss of appetite, and dizziness.

Brand Names

Lantrisul; Neotrizine; Sulfa-Triple #2; Sulfadiazine; Sulfaloid; Sulfonamides Duplex; Sulfose; Terfonyl; Triple Sulfa; Triple Sulfas; Triple Sulfoid

See also



 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Sulfadiazine". A list of authors is available in Wikipedia.
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