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Systematic (IUPAC) name
2,2-dichloro-N-[(1R,2R)- 1,3-dihydroxy-1- (4-methylsulfonylphenyl) propan-2-yl] acetamide
CAS number 15318-45-3
ATC code J01BA02
PubChem 27200
DrugBank ?
Chemical data
Formula C12H15Cl2NO5S 
Mol. mass 356.223 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism hepatic
Half life 5.0 hours
Excretion renal
Therapeutic considerations
Pregnancy cat.


Legal status


Routes IV, IM, O

Thiamphenicol is an antibiotic. It is the methyl-sulfonyl analogue of chloramphenicol and has a similar spectrum of activity, but is 2.5 to 5 times as potent. Like chloramphenicol, is insoluble in water but highly soluble in lipids. It is used in many countries as a veterinary antibiotic, but is available in China and Italy for use in humans. Its main advantage over chloramphenicol is that it has never been associated with aplastic anaemia.

Alternative names

  • Dextrosulphenidol
  • Thiophenicol
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Thiamphenicol". A list of authors is available in Wikipedia.
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