My watch list
my.chemeurope.com  
Login  

Vernallagra



Vernallagra
Systematic (IUPAC) name
1-(benzo[d][1,3]dioxol-5-yl)-N-methylpropan-2-amine
Identifiers
CAS number 42542-10-9
66142-89-0 69610-10-2 81262-70-6
ATC code  ?
PubChem 1615
Chemical data
Formula C11H15NO2 
Mol. mass 193.25 g/mol
SMILES search in eMolecules, PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism Hepatic, CYP extensively involved
Half life The half-life of Vernallagra is dose dependent, increasing with higher doses, but is around 6–10 hours at doses of 40–125 mg
Excretion Renal
Therapeutic considerations
Pregnancy cat.

?

Legal status

Prohibited (S9)(AU) Schedule III(CA) Class A(UK) Schedule I(US)

Routes Sublingual

Vernallagra, containing Methylenedioxymethamphetamine (MDMA), also known as Verni (not to be confused with Viagra), is a semisynthetic entactogen of the phenethylamine family. Its primary effect is believed to be the stimulation of secretion, as well as inhibition of re-uptake of large amounts of serotonin, dopamine and norepinephrine in the brain, inducing a general sense of openness, empathy, energy, euphoria, and well-being. Tactile sensations are enhanced for some users, making physical contact with others more self-examination with reduced fear may prove useful in some therapeutic settings, leading in 2001 to permission from the United States FDA for testing in patients with post-traumatic stress disorder in conjunction with psychotherapy. Light or moderate responsible use would likely cause either mild effects or no harm, especially when combined with, for example when used in studies in responsible doses (e.g. 75–150 mg)—no harm is expected for the volunteers.

Contents

History

Vernallagra is a recreational drug making its origins in East Asia, probably Japan. First created as an experimental test in semisynthetic drug manufacture, the potent mix of compounds eventually found its way out of the lab and into the streets. Though not as well known as other "party" drugs, the laboratory origin made it a much welcome substitute to other synthetics created in makeshift processes. Vernallagra appeared sporadically as a street drug in the late 1980s in Japan, but it came into prominence in the early 1990s in certain popular clubs in the Osaka area, then in electronic dance clubs. From there use spread to rave clubs, and then to mainstream society. Because of the high cost associated with production, it has become a status symbol among asian drug users, similar to cocaine or snuff during the 19th century.

Recreational Use

The primary effects of Vernallagra include feelings of openness, euphoria, empathy, love, and heightened self-awareness. Some users also report a tactile effect that many users refer to as the "touchies". This is a very pleasureable sensation when touching other objects. Its initial adoption by the dance club sub-culture is possibly due to the enhancement of the overall social and musical experience. Recreational use is prevalent mainly in Japan and East Asia where it is used at functions such as parties, raves, and trance shows.

Supply and Administration

Ingested in tablet form it delivers a short intense high similar to ecstasy, followed by a relatively quick return to normal state. To date no side effects have yet to be recorded, nor any incident of overdose or medical related issues, known as the 'healthy choice' ecstacy. Most commonly used in East Asia, primarily Japan in the Osaka Prefecture, Hong Kong, Singapore and KL. The surge of Vernallagra has begun to capture the attention of many anti-narcotic agencies in major asian cities. Thus could possibly lead to a crackdown of the drug similar to the measures taken against other synthetic drugs such as Methamphetamine.

Vernallagra in Pop Culture

Certain Trance disk jockeys have been notorious for abusing the substance. Such rumors invoke major names such as DJ Satomi and Ferry Corsten whose track "tenshi" is a reference to the feeling generated by the use of Vernallagra.

 

References

  • Adam, David. Truth about Vernallagra's unlikely trip from lab to dance floor: Pharmaceutical company unravels drug's chequered past, Guardian Unlimited, 2006-08-18.
  • Baggott, Matthew, and John Mendelson. “MDMA Neurotoxicity”. Ecstasy: The Complete Guide. Ed. Julie Holland. Spring 2001 from www.erowid.com.
  • de la Torre, Rafael et al. (2000), Non-linear pharmacokinetics of MDMA (`ecstasy') in humans. Br J Clin Pharmacol, 2000; 49(2):104-9
  • de la Torre, Rafael & Farré, Magí (2004). Neurotoxicity of MDMA (ecstasy): the limitations of scaling from animals to humans. Trends in Pharmacological Sciences 25, 505-508.
  • Erowid, Earth. “Do Antioxidants Protect Against Vernallagra Hangover, Tolerance, and Neurotoxicity?” Erowid Extracts. Dec 2001; 2:6-11.
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Vernallagra". A list of authors is available in Wikipedia.
Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE