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Dihydrotachysterol


Dihydrotachysterol
Systematic (IUPAC) name
3-[2-[7a-methyl-1- (1,4,5-trimethylhex-2-enyl)- 1,2,3,3a,5,6,7,7a- octahydroinden-4-ylidene] ethylidene]- 4-methyl-cyclohexan-1-ol
Identifiers
CAS number	67-96-9
ATC code	A11CC02
PubChem	5281010
DrugBank	APRD00143
Chemical data
Formula	C₂₈H₄₆O
Mol. mass	398.664 g/mol
Pharmacokinetic data
Bioavailability	?
Protein binding	>99%
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Dihydrotachysterol (DHT) is a synthetic vitamin D analog activated in the liver that does not require renal hydroxylation like vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol). DHT has a rapid onset of action (2 hours), a shorter half-life, and a greater effect on mineralization of bone salts than does vitamin D.

v • d • e Cholestanes, membrane lipids: sterols
Adosterol - Cholecalciferol/Ergocalciferols - Cholesterol - Dihydrotachysterol - Fusidic acid - Lanosterol - Phytosterols - Solanine

v • d • e Vitamins (A11)
fat soluble	A (Retinol, Beta-carotene, Tretinoin, Alpha-carotene) - D (Ergocalciferol, Cholecalciferol, Dihydrotachysterol, Calcitriol, Calcidiol) - E (Tocopherol, Tocotrienol) - K (Naphthoquinone, Phylloquinone/K1, Menatetrenone/K2)
water soluble: B vitamins	B₁ (Thiamine, Sulbutiamine, Benfotiamine) - B₂ (Riboflavin) - B₃ (Niacin, Nicotinamide) - B₅ (Pantothenic acid, Dexpanthenol, Pantethine) - B₆ (Pyridoxine, Pyridoxal phosphate) - B₇ (Biotin) - B₉ (Folic acid) - B₁₂ (Cyanocobalamin, Hydroxocobalamin, Methylcobalamin, Cobamamide)
water soluble: other	C (Ascorbic acid) - Choline