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The distribution of a drug between tissues is dependent on permeability between tissues (between blood and tissues in particular), blood flow and perfusion rate of the tissue and the ability of the drug to bind plasma proteins and tissue. pH parturition plays a major role as well.
The volume of distribution (VD) of a drug is a property that quantifies the extent of distribution.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Distribution_(pharmacology)". A list of authors is available in Wikipedia.|